AANA19 Shoulder Access Pass-The Basic Science of Rotator Cuff Disease_ Biologic Basis of Muscle, Tendon and Bone-Dr. Andrew Frederic Kuntz, M.D.

The Basic Science of Rotator Cuff Disease_ Biologic Basis of Muscle, Tendon and Bone-Dr. Andrew Frederic Kuntz, M.D.

Video Transcription

Video Summary

The talk discusses rotator cuff disease's basic science, focusing on tendon, muscle, and bone. It highlights the unique enthesis structure, crucial for force transmission between tendon and bone, which is not restored after rotator cuff repair, leading to high failure rates. Both intrinsic factors (like vascularity, collagen, aging, comorbidities such as hyperlipidemia) and extrinsic factors (such as impingement and scapular dyskinesis) affect tendon health and healing. Bone density loss and muscle atrophy with fatty infiltration worsen outcomes, and current research targets growth factor pathways to improve recovery. Understanding these mechanisms is vital for developing better treatments.

Keywords

rotator cuff disease

enthesis structure

tendon healing factors

bone density loss

growth factor pathways