AANA19 Knee Access Pass-BEAR Early Outcomes-Dr. Martha Murray, M.D.

BEAR Early Outcomes-Dr. Martha Murray, M.D.

Video Transcription

Video Summary

The speaker, founder of Neoc Orthopedics, discussed their FDA-approved scaffold for ACL repair, which addresses challenges with traditional ACL repairs, notably gap formation that impedes healing. Their scaffold promotes ligament cell migration, has optimized resorption, and minimizes immune reactions. Animal studies showed restored ligament histology, comparable strength to grafts, and preserved cartilage. In the BARE-1 human trial with 20 patients, outcomes showed no revisions, infections, or rejections at two years, with better knee stability, hamstring strength, and ACL anatomy versus reconstruction. The positive results support further studies in ongoing BARE trials.

Keywords

FDA-approved scaffold

ACL repair

ligament cell migration

BARE-1 human trial

knee stability