AANA19 Foot & Ankle Access Pass-OCD update-Dr. Richard D. Ferkel, M.D.

Video Transcription

Video Summary

The presentation reviewed current cartilage transplant techniques for osteochondral lesions, focusing on matrix-induced autologous chondrocyte implantation (MACI), juvenile particulate cartilage allografts, micronized cartilage matrix, and emerging cell-based therapies. MACI, approved in 2017, shows promise especially with bone cysts using a “sandwich” grafting approach. Juvenile cartilage allografts offer good mid-term outcomes but require longer studies. Micronized cartilage is convenient and cost-effective but lacks long-term data. New stem-cell-based therapies like Miami cells are experimental. Metal implants help salvage failed cases but carry high reoperation rates. A global consensus emphasizes ongoing challenges and future goals for improved, less invasive cartilage restoration.

Keywords

cartilage transplant

osteochondral lesions

matrix-induced autologous chondrocyte implantation

juvenile particulate cartilage allografts

stem-cell-based therapies