AANA Knee Arthroscopy - September 2024-Orthobiologic Injections: How I Use in My Practice

Orthobiologic Injections: How I Use in My Practice

Video Transcription

Video Summary

Dr. Bert Mandelbaum discusses the evolving use of orthobiologic injections for tendon, ligament, cartilage, and osteoarthritis treatments. Emphasizing evidence-based practice and FDA guidelines, he reviews data supporting platelet-rich plasma (PRP) for patellar tendon, MCL injuries, meniscus repair, and osteoarthritis, often giving a "green light" rating. PRP combined with hyaluronic acid shows synergistic benefits. Bone marrow aspirate concentrate (BMAC) and stem cells remain experimental ("yellow" or "red" light). Emerging therapies like exosomes, amniotic fluid, estrogen, and WNT inhibitors are promising but require more research. He stresses cautious, ethical application, bridging hope and knowledge wisely.

Asset Caption

Dr. Bert Mandelbaum

Keywords

orthobiologic injections

platelet-rich plasma

osteoarthritis treatment

bone marrow aspirate concentrate

emerging therapies