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Biologics for Chronic Tendinopathy
Biologics for Chronic Tendinopathy
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Video Transcription
Video Summary
Jason Jagoo from the University of Colorado discusses tendinopathy, revealing that affected tendon cells lose the ability to produce and respond to their environment, shifting to an inflammatory state due to genetic alterations. Traditional treatments like PRP show limited success, as they don't reverse these cellular changes. Bone marrow aspirate concentrate (BMAC) shows promise in restoring cell function and tendon structure, though results vary by patient. In cases where biologics are insufficient, surgical approaches, including arthroscopy and tendon scraping, may be needed. Overall, tendinopathy remains challenging, with future therapies potentially focusing on optimized biologic dosing and tailored interventions.
Asset Caption
Jason L. Dragoo, M.D., FAANA
Keywords
tendinopathy
inflammatory state
PRP treatment
bone marrow aspirate concentrate
surgical interventions
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