2023 Annual Meeting Biologics-Cartilage Pearl

Video Transcription

Video Summary

Shachin Alhabadi presented key techniques to optimize osteochondral allograft healing and clinical success. He emphasized gradual warming of cold-preserved grafts to improve chondrocyte activity, reaming grafts submerged in saline to reduce thermal necrosis, and precise control of subchondral bone depth (5-8mm) to balance immunogenicity and cyst formation. Bone edges are chamfered, with grooves added to ease insertion and removal. High-pressure pulse lavage combined with pressurized carbon dioxide significantly reduces marrow elements and immunogenicity while improving orthobiologic absorption. Hydrating grafts with bone marrow aspirate concentrate enhances outcomes. Gentle graft insertion with limited impaction preserves cell viability, promoting better healing.

Asset Caption

Sachin Allahbahdi, M.D.

Keywords

osteochondral allograft

chondrocyte activity

subchondral bone depth

high-pressure pulse lavage

bone marrow aspirate concentrate