2021 Annual Meeting Knee Access Pass-Questions and Answers: Knee Cartilage

Video Transcription

Video Summary

The discussion centers on advanced cartilage repair techniques, combining microfracture with peripheral blood mobilization using GCSF (filgrastim) to enhance progenitor cell availability. The protocol involves low-dose GCSF post-surgery to harvest pluripotent cells aiding cartilage maturation. Safety concerns about GCSF are minimal compared to oncology use. Other topics include pain management in outpatient osteotomies, emphasizing multimodal strategies and surgeon preparedness, especially without hospital affiliation. The role of ACE inhibitors like losartan in cartilage repair via TGF-beta pathways is also discussed. Overall, these innovations and protocols aim to improve orthopedic outcomes while ensuring patient safety.

Asset Caption

Adam Anz; Catherine Logan, MD, MSPT, MBAB; Michael Alaia, MD; Yudai Morita, MD

Keywords

cartilage repair

microfracture technique

GCSF (filgrastim)

pain management in osteotomies

ACE inhibitors in cartilage repair