2021 AANA/ASES Specialty Session-It’s All About the Biology: Biologic Adjuncts for the Rotator Cuff at Risk

It’s All About the Biology: Biologic Adjuncts for the Rotator Cuff at Risk

Video Transcription

Video Summary

This presentation reviews biological adjuncts for rotator cuff repair and tendinopathy, emphasizing cautious use of unproven therapies. Platelet-rich plasma (PRP) shows inconsistent benefits for tendinopathy but may improve structural healing post-repair, though no consensus on formulation exists. Platelet-rich fibrin matrix is not recommended due to negative effects. Cell therapy, particularly with adipose-derived cells, shows promise for enhancing tendon healing but requires further research. Systemic factors like vitamin D deficiency negatively affect healing; supplementation is advised. Parathyroid hormone and other metabolic agents hold potential yet need validation. Lifestyle factors—smoking, obesity, cholesterol, diabetes—also impact outcomes and should be managed.

Asset Caption

Scott A. Rodeo, M.D.

Keywords

rotator cuff repair

tendinopathy

platelet-rich plasma

cell therapy

vitamin D deficiency